Pre-Marital Tests

Premarital Genetic Screening

Premarital screening is a group of tests recommended for couples that are going to get married, to prevent as much as possible transmitting disease to their offspring.

Premarital or preconception tests include testing for genetic, infectious and blood transmitted diseases.

Premarital screening varies from one region to another depending on the prevalence of the diseases in that region. From these tests, there are some more specific for the gulf region, for example testing for sickle cell disease and thalassemia.

Premarital screening test includes the following:

• Complete blood count (CBC)
• Blood group (ABO & Rh typing)
• Hb Variants testing (Thalassemia, Sickle cell)
• G6PD
• Sexually transmitted diseases
  • HIV
  • Hepatitis B
  • Hepatitis C
  • Syphilis
  • Other STDs (i.e gonorrhea, Chlamydia …)

Other testing might include :

• Male and Female fertility testing
• Karyotyping

Premarital genetic testing may be necessary if the spouses come from related families or are directly related (consanguineous) and mainly in couples with known genetic diseases in the family to find out if there is a chance for their children to be affected by this disease.

Sample Reports:

• General blood tests (e.g. blood group, hemoglobin studies)
• STD and infectious disease testing (see STD Panel Test)
• Hormone testing, semen analysis, ovarian function (see Fertility)
• Chromosome analysis  (see Fertility)

References:

1. Six years of premarital screening in Saudi Arabia markedly reduced the number of at-risk marriages

2. A study on knowledge towards premarital screening among adults in Oman

FAQ:

1. Why is premarital screening important?

Premarital screening is a health check-up designed to identify genetic, infectious, and chronic conditions in both partners. It's important because it helps detect potential health risks that could impact a couple’s future or their plans for having children.

2. Are there region-specific tests in premarital screening?

Yes, premarital screening varies by region based on disease prevalence.

Testing for sickle cell disease and thalassemia in the Gulf region is more specific due to their higher occurrence.

3. Who should consider premarital genetic testing?

It's particularly recommended for couples from related families (consanguineous marriages) or those with a known family history of genetic diseases, to assess the risk of passing these conditions to their children.

4 . Are there additional tests recommended for specific individuals?

Yes, additional testing might include male and female fertility testing and karyotyping, especially if there is a family history of genetic diseases or if the couple is consanguineous (related by blood).

5. Why is a Thalassemia screen important in premarital screening?

Thalassemia is a hereditary blood disorder. If both partners are carriers, their children may inherit severe forms of the disease. Screening helps couples assess genetic risks and make informed family planning decisions

6. Is premarital screening only for couples planning to have children?

Premarital screening can benefit all couples, regardless of their plans for children. It evaluates overall health and potential risks, ensuring both partners are fully informed of their health status before marriage.

7. What Documents Are Required for the Premarital Screening?

The following documents are required for the Premarital Screening:

● A valid Emirates ID or passport

● A completed and signed marriage application form

● A copy of both parties' passports or Emirates IDs

● Pre-nuptial agreement (if applicable)

Please contact us if you wish to have a consultation with one of our pathologists.